Work

Surfactant and surfactant therapy in neonates: from the beginning to the modern features of the application

Year: 2025

Type: article

Abstract: Surfactant is a secreted surface-active substance that provides the first breath of the newborn by reducing the surface tension of the alveoli. Surfactant preparations were the first and most popular drugs in neonatology, saving the lives of millions of premature babies. Successful treatment with surfactants is preceded by an individual personalized approach to each child and early detection of newborns with surfactant deficiency. Determining the indications for surfactant therapy, choosing an effective method of drug delivery, selecting concomitant respiratory support are current areas of neonatology to this day. The article reflects the history of use, new approaches to surfactant therapy and methods of administration of various surfactant preparations.

Source: Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)

DOI: 10.21508/1027-4065-2025-70-2(p.2)-5-16

Authors: K. S. Zizyukina, H. A. Sarkisyan, L. D. Vorona, L. A. Levchenko, E. I. Shabelnikova, A. P. Khokhlova, Sh. T. Abasova, P. V. Shumilov

Institutions: Pirogov Russian National Research Medical University, Children's City Clinical Hospital No. 9

Language: English

Topic: Neonatal Respiratory Health Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4409847465

FWCI: 1.181

Cites: 53

Cited by: 2

Related to: 10