Work

Urinary Ammonium: A Potential Novel Biomarker for Diarrhea Severity in Patients With Ulcerative Colitis

Year: 2025

Type: article

Abstract: Almost 3 million outpatient visits to gastroenterology clinics are prompted by diarrhea as the chief complaint, yet evaluating its severity remains inherently subjective.1 Self-reported symptoms often fail to accurately quantify diarrheal losses due to factors such as bowel frequency, urgency, and incomplete evacuation.2,3 Objective biomarkers offer a standardized, reproducible measure that reduces reliance on subjective self-reports like stool frequency, minimizing recall bias and variability in clinical assessment.

Source: Gastro Hep Advances

DOI: 10.1016/j.gastha.2025.100686

Authors: Jared A. Sninsky, L. Parker Gregg, Mahbubur Rahman, Adith Ram, Jason K. Hou

Institutions: Michael E. DeBakey VA Medical Center, Baylor College of Medicine, Mental Illness Research, Education and Clinical Centers

Language: English

Topic: Inflammatory Bowel Disease

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,000