Protected Specimen Brush (PSB) or Bronchoalveolar Lavage (BAL) for Diagnosing Ventilator-Associated Pneumonia
Year: 2024
Type: article
Study design: Observational Study
Abstract: Background: Ventilator-associated pneumonia (VAP) is a common and serious infection in intubated patients, leading to increased mortality, longer ICU stays, and higher healthcare costs. Accurate diagnosis is essential for effective treatment and to prevent antibiotic misuse.Purpose: This study investigates whether bronchoalveolar lavage (BAL) and protected specimen brush (PSB) yield similar culture results in ICU patients with suspected or confirmed VAP.Methods: A retrospective study was conducted on ICU patients with VAP at Shar Hospital, Sulaymaniyah, Iraq, from 2020 to 2023. Patients on ventilators for ≥48 hours with new lung infiltrates who underwent both BAL and PSB were included. Spearman's correlation was used to compare culture results.Results: Out of 56 VAP patients, 20 met inclusion criteria. Bacteria were detected in 48% of BAL and 43% of PSB samples. A significant correlation was found between BAL and PSB results (correlation coefficient 0.846, p < 0.01), with 96% agreement in detected agents.Conclusion: PSB and BAL provide comparable results for diagnosing VAP, but PSB might be preferred due to its specificity and lower risk of procedural complications. Correct BAL technique, involving adequate saline flushing, is essential for accurate results. Further studies should standardize BAL procedures to optimize diagnostic accuracy
Authors: Haval Othman Ali, Kawa Wsu Hassan
Language: English
Topic: Nosocomial Infections in ICU
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4409853980