Work

You are what you eat: metabolic recycling of phagocytosed bacteria modulates macrophage immunity

Year: 2025

Type: article

Abstract: In a recent study published in Nature , Lesbats et al. 1 show that phagocytosed bacteria can be recycled by macrophages to serve as an alternative nutrient source. Bacterial cAMP was identified as a signal for macrophages to differentiate between dead and live bacteria and to adjust the inflammatory response accordingly.

Source: Signal Transduction and Targeted Therapy

DOI: 10.1038/s41392-025-02222-x

Authors: Syamantak Basu, Manuela Rossol

Institution: Brandenburg University of Technology Cottbus-Senftenberg

Language: English

Topic: Phagocytosis and Immune Regulation

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,790