Association between Duration of Early Empiric Antibiotics and Necrotizing Enterocolitis and Late-Onset Sepsis in Preterm Infants
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: Early empiric antibiotic exposure (EEAE) is a common practice in neonatal intensive care units (NICUs) to prevent infections in preterm infants. However, concerns have arisen regarding its potential association with adverse outcomes, including necrotizing enterocolitis (NEC) and late-onset sepsis (LOS). This study aims to evaluate the relationship between EEAE and the incidence of NEC and LOS in preterm infants. Methods: A comparative cross-sectional study was conducted involving 48 preterm neonates admitted to the NICU from January to August 2024. Participants were divided into two groups based on the duration of EAE: Group I those receiving prolonged antibiotics (>7days)and GroupII those receiving short-term antibiotics(
Source: Benha Medical Journal
Authors: Mona Hassan Mohamed, Ahmed Mahmoud Ezzat, Effat Hussein Assar, yasser mahmoud ismail, Mohamed Mahmoud Shehab
Institutions: Benha University, Zagazig University
Language: English
Topic: Infant Nutrition and Health
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4409863272