Work

Intracellular metabolic gradients dictate dependence on exogenous pyruvate

Year: 2025

Type: article

Source: Nature Metabolism

DOI: 10.1038/s42255-025-01289-8

Authors: Benjamin T. Jackson, Angela M. Montero, Sangita Chakraborty, Julia S. Brunner, Paige K. Arnold, Anna E. Bridgeman, Pavlina K. Todorova, Katrina I. Paras, Lydia W. S. Finley

Institutions: Memorial Sloan Kettering Cancer Center, Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences, Cornell University, Weill Cornell Medicine

Language: English

Topic: Cancer, Hypoxia, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Health and Human Services, New York Stem Cell Foundation, Human Frontier Science Program, National Cancer Institute, National Institute of General Medical Sciences, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: G1007166040, G152002331, Coupling metabolic pathways with pluripotent gene regulation in mouse embryonic stem cells, Training Program in Developmental and Stem Cell Biology, G471198185, G4799314940, G554736477, G6469656094, Cancer Center Support Grant, Weill Cornell/Rockefeller/Sloan Kettering MST Program, Metabolic control of exit from naïve pluripotency

OpenAlex ID: W4409868678

FWCI: 4.47

Cites: 73

Cited by: 10

Related to: 10