[MÖB-01] Study of the Effect of Fat Mass Index and Fat Free Mass Index on Postoperative Complications and Hospitalization in Patients Undergoing Isolated Coronary Artery Bypass Grafting Operation
Year: 2024
Type: article
Study design: Observational Study
Abstract: Objective: This study aimed to investigate the effect of preoperative fat mass and fat-free mass measurements on postoperative morbidity and mortality in patients scheduled for coronary artery bypass grafting (CABG). Methods: In the prospective study conducted preoperative biochemistry analyses, sex, age, height, weight, body mass index, body surface area, fat mass index (FMI), fat-free mass index (FFMI), fat mass ratio (FMR), and fat-free mass ratio (FFMR) of 120 individuals were recorded. The number of vessels with CABG, postoperative need for inotropic drugs, time of extubation, total duration of intubation, duration of intensive care unit stay, duration of hospitalization, presence of wound drainage, cases of revision, development of pulmonary embolism, postoperative atrial fibrillation, ventricular arrhythmia, postoperative need for an intra-aortic balloon pump and extracorporeal membrane oxygenation, and death. For FMR, FFMR, and FMI, thresholds were determined by receiver operating characteristic analyses on wound drainage. The FFMI was evaluated within the ranges of 18.7 to 21 kg/m 2 in males and 14.9 to 17.2 kg/m 2 in females. Results: Receiver operating characteristic analysis yielded the following thresholds: FMR, 0.26; FFMR, 0.73; and FMI, 7.46. Sex, age, body mass index, hypertension, diabetes, the need for postoperative continuous positive airway pressure or Vapotherm, wound drainage, need for inotropes, intensive care, and length of hospitalization were observed to be associated with FMI, FMR, and FFMR. Furthermore, FMR and FFMR were associated with pulmonary embolism. Patients with FFMI in the normal range had significantly less atrial fibrillation and wound drainage. Conclusion: Preoperative fat mass measurements (FMI, FMR, FFMR, and FFMI) could effectively predict postoperative morbidity and mortality in patients after CABG. The findings underscore the importance of including fat and fat-free masses in operative risk calculations, as it can significantly enhance the accuracy of predicting complications, improving patient outcomes.
Institution: Marmara University
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4409891333