Work

Topoisomerase IIα-mediated stemness response in reactive astrocytes to traumatic brain injury

Year: 2025

Type: article

Abstract: This study identifies TOP2a as a pivotal intrinsic regulator of astrocytic stem cell potential in the injured brain, which will advance our understanding of the molecular underpinnings of the stem cell response and its therapeutic application in neural regeneration.

Source: Theranostics

DOI: 10.7150/thno.111923

Authors: Shangyao Qin, Xiao Huang, Yimin Yuan, Hong Liu, Jiali Li, Ziwei Dai, Zhida Lan, Yingyan Pu, Cheng He, Zhida Su

Institutions: Second Military Medical University, University of Electronic Science and Technology of China, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital

Language: English

Topic: Neurogenesis and neuroplasticity mechanisms

Subfield: Developmental Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,671

OpenAlex ID: W4409898755

FWCI: 0.358

Cites: 1

Cited by: 1

Related to: 10