Work

A new bisbenzylisoquinoline alkaloid from the roots of Stephania tetrandra

Year: 2025

Type: article

Abstract: A new bisbenzylisoquinoline alkaloid, (1S,1′S)‐13‐hydroxy‐6,6′,7‐trimethoxy‐2,2′‐dimethylberbaman (1) along with four known alkaloids, tetrandrine (2), fangchinoline (3), tetrahydropalmatine (4) and dehydrocrebanine (5) were isolated from the roots of Stephania tetrandra. Their chemical structure was determined by HR‐ESI‐MS and 1D‐, 2D NMR spectra and comparison with published results. The absolute configuration of compound 1 was determined by the electronic circular dichroism (ECD) spectroscopy technique.

Source: Vietnam Journal of Chemistry

DOI: 10.1002/vjch.70026

Authors: Nguyen Thanh Tam, Dao Duc Thien, Le Quoc Thang

Institutions: Graduate University of Science and Technology, Viện Hóa học, Vietnam Academy of Science and Technology, Hue University, Hue University of Education

Language: English

Topic: Berberine and alkaloids research

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

Open Access status: gold

Estimated APC paid: $3,400

Funder: Vietnam Academy of Science and Technology