Acute Symmetric Arterial Thrombosis of the Four Extremities Associated with Pregnancy: Case Report
Year: 2025
Type: article
Study design: Case Report
Abstract: During the normal process of pregnancy, there is a procoagulant state derived from the alteration of all the components of the Virchow Triad. Multiple biochemical and structural changes lead to an increased risk of thromboembolic events. Although venous embolic events are more common, arterial thrombosis generally leads to devastating outcomes. Anticoagulation in pregnant patients has very specific indications, primarily in patients with a history of thromboembolism or poor obstetric history. There are multiple drugs used for venous or arterial thrombosis, some of which are associated with teratogenic effects, the most commonly used being low molecular weight heparin. In cases of valve prosthesis and antiphospholipid syndrome, antiplatelet drugs should be added. Shock is the main cause of admission and mortality in intensive care units. In the absence of myocardial dysfunction, hypotension is primarily caused by hypovolemia and the physiological inability to self-regulate and adequately perfuse. In these cases, there are guidelines for the use of vasopressors, aimed at maintaining adequate perfusion to essential organs. However, the use of these drugs may be associated with adverse effects, including the possibility of ischemia in some anatomical regions. In this article, we present the case of a multi-pregnant patient with the presence of several etiopathogenic factors that triggered distal necrosis of all four extremities, requiring amputation.
Authors: Residente de tercer año del Servicio de Cirugía Plástica y Reconstructiva en el Centro Medico Licenciado Adolfo López Mateos., Jorge Elpidio Moreno Carranza, Manuel Suarez Ortega, Residente de segundo año del Servicio de Cirugía Plástica y Reconstructiva en el Centro Medico Licenciado Adolfo López Mateos., Jesús Fernando Romero Espinosa, Jefe del Servicio de Cirugía Plástica y Reconstructiva en el Centro Medico Licenciado Adolfo López Mateos., Josué Eder Albavera Gutierrez, IMSS HGZ #1 Emilio Varela Luján, Zacatecas, Zacatecas., Ivonne Alejandra Perales Soto, Universidad Autónoma de Baja California, Escuela de Ciencias de la Salud, Campus Ensenada, Unidad Valle Dorado., Álvaro Sebastián Gutierrez Macklis, Universidad Autónoma de Baja California, Escuela de Ciencias de la Salud, Campus Ensenada, Unidad Valle Dorado., Alberto Jaramillo Sastré, Facultad de medicina UNAM., Jesús Alejandro Olvera Rodríguez, Jorge Manuel Montelongo Hernández, López Barba Jonathan Nadiell, Universidad de Guadalajara., Hannah Naomi Ortega Aranda, Centro Médico ABC, Eduardo Aldayr Quiroz Diaz, Universidad de la Salud del estado de México (UNSA)., Fernando Miguel Quiroz Diaz, Unidad Médica de Alta Especialidad 14 IMSS., Leonardo Esteban Mata Sansores, Unidad Médica de Alta Especialidad 14 IMSS., Joselyn Ugalde Rivera, Karen Vanessa García Espinoza, Jorge Alan Lara Urbina
Language: English
Subfield: Internal Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4409903303