Challenging trends in clinical-epidemiology and sero-prevalence of leptospirosis among febrile patients
Year: 2025
Type: article
Study design: Observational Study
Abstract: Leptospirosis is the most prevalent zoonotic illness that affects both humans and animals worldwide. It is typically underreported due to a lack of knowledge, unusual manifestations and a lack of diagnostic resources. Therefore, it is of interest to estimate the seroprevalence of Leptospirosis from an acute febrile illness patient at a tertiary care hospital in India. Hence, a total of 252 blood samples were collected out of which 39 (15.47%) were positive for leptospirosis IgM antibody. Male patient (56.75%) shows preponderance over females. Further patients among the age group groups 21-40 (56.41%) showed the positivity. A clinical presentation such as Fever (100%), Myalgia (51.5%) and Headache (36.98%) was the most common symptoms seen followed by vomiting and abdominal pain. Leptospirosis screening must therefore be introduced as differential diagnosis in individuals with acute fever in addition to other routine testing in order to lower the morbidity and mortality.
Source: Bioinformation
Authors: Akila Krishnamoorthy, Kamalraj Mohan, Sijimol Shanmughan, Subha Vajjiravel Jagganath, Anitha Srinivasagalu, Ambuja Sekhar, Senthamarai Srinivasan, Sivasankari Selvaraj
Language: English
Subfield: Parasitology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W4409903998