Year: 2025
Type: article
Study design: Case Report
Abstract: Atenolol is a cardio selective beta-blocker and its toxicity often leads to severe hemodynamic instability and contributes to mortality. A significant number of fatal poisonings are caused by beta blockers and supportive therapy is the cornerstone of treatment. We report a case of atenolol toxicity, who had bradycardia and severe hypotension. The patient was administered with high dose insulin therapy, glucagon infusion, lipid emulsion therapy and vasopressors to maintain the mean arterial pressure (MAP) and normal heart rate. Despite these, the patient did not show any clinical improvement. Owing to the favourable hydrophilic and pharmacokinetic characteristics of atenolol, we have administered hemodialysis treatment, with which subsequent improvement in hemodynamic and clinical parameters were observed. The management of atenolol overdose was thus successful with hemodialysis.
Authors: Abhishek Chintamani, Madhusudan R. Jaju
Institution: Yashoda Hospital
Language: English
Subfield: Emergency Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4409908976