Year: 2024
Type: article
Abstract: Classical gene therapy, as a new therapeutic means acting on the genome, has become the frontier hot spot and research focus in the field of biotechnology and medicine. Its basic principle is to repair or replace defective genes in the body by directly delivering foreign genes to human cells, so as to achieve the purpose of treating diseases.With the deepening of the research of classical gene therapy, mRNA drug therapy has gradually been summarized as a new type of gene therapy, and occupies an important position.Different from classical gene therapy, mRNA drug therapy is more focused on directly manipulating mRNA molecules to achieve protein production to complete the treatment.Due to the increasing investment in research and application of mRNA drug therapy, classical gene therapy and mRNA drug therapy have become more selective in the treatment of diseases. This article will deeply discuss the differences in development, principle and application direction of the two, explore their respective advantages, and provide ideas and basis for the optimal selection of disease treatment programs in the future.
Author: Xie Xinyu
Institution: Henan University of Technology
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W4409909029