Contrast-enhanced ultrasound combined with shear wave elastography in the diagnosis of C-TIRADS category 4 thyroid nodules
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: Contrast-enhanced ultrasound (CEUS) and shear wave elastography (SWE) have been widely used in the diagnosis of thyroid nodules. The main purpose of this study was to investigate the diagnostic value of CEUS combined with SWE for Chinese Thyroid Imaging Reporting and Data System (C-TIRADS) category 4 thyroid nodules. Methods: CEUS and SWE were performed on 219 patients with 219 C-TIRADS category 4 thyroid nodules. Receiver operator characteristic (ROC) curves were drawn based on the surgical and pathological results. The diagnostic efficacy of CEUS, SWE, and CEUS and SWE combined were analyzed and compared. Results: ) of CEUS were 81.0% (136/168), 86.3% (44/51), 82.2% (180/219), 57.9% (44/76), 95.1% (136/143), 5.90, and 0.22, respectively, while those of SWE were 78.6% (132/168), 74.5% (38/51), 77.6% (170/219), 51.4% (38/74), 91.0% (132/145), 3.08, and 0.29, respectively, and those of CEUS and SWE combined were 94.6% (159/168), 84.3% (43/51), 92.2% (202/219), 82.7% (43/52), 95.2% (159/167), 6.03, and 0.06, respectively. After CEUS and SWE combined, the diagnostic sensitivity, NPV, and accuracy were improved (all P<0.05). Conclusions: For C-TIRADS category 4 thyroid nodules, CEUS and SWE had high diagnostic efficacy, and the combination of CEUS and SWE further increased the diagnostic sensitivity, NPV, and accuracy, and thus could be used to help guide the treatment and management of patients.
DOI: 10.21037/qims-24-666
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4409911225