Correlation analysis of organ doses with dose metrics for patients undergoing organ dose-modulated head CT examinations
Year: 2025
Type: article
Abstract: Background: The rapid advancement of computed tomography (CT) has greatly improved clinical diagnosis but has also introduced new challenges in radiation protection. This study aimed to evaluate the relationship between organ doses from Monte Carlo (MC) simulations and CT dose metrics for head CT exams with organ dose modulation (ODM), and to develop a simplified method for estimating individual organ doses. Methods: , size-specific dose estimate (SSDE), and organ-specific SSDE were derived based on the exposure (mAs) and water-equivalent diameters of each slice image. Linear regression fitting was used to explore the correlation between organ doses (including the brain, the eyeballs, the eye lens, and the salivary glands) and the four CT dose metrics mentioned above. Results: between each organ dose and corresponding organ-specific SSDE were 0.92 for the brain, 0.91 for eyeballs, 0.90 for the eye lens, and 0.90 for the salivary gland). Estimation coefficients for estimating organ doses of the brain, eyeballs, eye lens, and salivary glands from organ-specific SSDE were 0.34, 0.59, 0.48, and 0.26, respectively, as a mean across all patients. Conclusions: There is a strong correlation between organ dose and organ-specific SSDE in ODM head CT examinations. However, activating the ODM results in significant differences in estimation coefficients for head CT exams with a fixed tube current, which provides a practical way to determine organ doses for individual patients undergoing head CT scans.
Language: English
Topic: Radiation Dose and Imaging
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4409911620