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The Role of Presepsin in Differentiating Between Bacterial and Viral Infections in Young Infants With Fever of Unknown Origin on the Emergency Department

Year: 2025

Type: article

Abstract: Presepsin has limited discriminative value between bacterial and viral infections in young infants at the emergency department, because the majority of bacterial infections concern a urinary tract infection, in which plasma presepsin was not elevated. The diagnostic accuracy of presepsin for sepsis in this population could not be established due to a low incidence of sepsis cases.

Source: The Pediatric Infectious Disease Journal

DOI: 10.1097/inf.0000000000004837

Authors: Charlotte M. Nusman, Sarah M. Schouten, Sjoerd Nagelkerke, Maya W. Keuning, Dorine Borensztajn, Frans B. Plötz, Douwe H. Visser, Jeroen Hol

Institutions: Noordwest Ziekenhuisgroep, Emma Kinderziekenhuis, Amsterdam University Medical Centers, Tergooi

Language: English

Topic: Sepsis Diagnosis and Treatment

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4409927490

FWCI: 0.605

Cites: 12

Cited by: 1

Related to: 10