Health care costs and resource utilization among patients with myasthenia gravis in the United States
Year: 2025
Type: article
Study design: Observational Study
Abstract: BACKGROUND: Myasthenia gravis (MG) is a rare neuromuscular disorder with an estimated prevalence of 37 per 100,000 individuals in the United States. Despite patients with MG using a wide range of health care services, there is a lack of information regarding health care costs and health care resource utilization (HCRU). OBJECTIVE: To gain insight into the health care cost and HCRU associated with an MG diagnosis from the US payer perspective. METHODS: Patients with MG, defined by at least 2 claims for MG diagnoses, were identified from a commercial and Medicare claims database between 2016 and 2021. Controls who were never diagnosed with MG were matched at a 10:1 ratio with each patient with MG based on baseline demographic and clinical characteristics. The primary outcomes were 1-year total health care costs associated with MG diagnosis, and the secondary outcomes were 1-year HCRU associated with MG diagnosis. Difference-in-difference estimates from a multivariable linear regression model were used to report adjusted health care costs and HCRU. RESULTS: < 0.01). MG diagnosis had significant impacts on HCRU across all health care settings. CONCLUSIONS: We quantified a significant increase in health care costs and HCRU in the first year following diagnosis of MG compared with the matched cohort. Future studies can further investigate long-term health care costs associated with patients with MG.
Authors: Sun A. Choi, Daniel R. Touchette, Kibum Kim
Institution: University of Illinois Chicago
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4409942742