Work

Gold-Catalyzed Migratory Insertion of Alkynes

Year: 2025

Type: article

Abstract: Herein, for the first time, we disclose the migratory insertion of alkynes into Au(III)‒C bonds in a catalytic fashion. Experimental results clearly suggest that the migratory insertion pathway predominates over the π-activation pathway - a finding further supported by the Density Functional Theory (DFT) calculations. The observed regioselectivity underscores the distinct advantages and complementarity of gold catalysis in comparison to palladium catalysis.

Source: ACS Catalysis

DOI: 10.1021/acscatal.5c01141

Authors: Avishek Das, Biswajit Biswas, Vincent Gandon, Nitin T. Patil

Institutions: Indian Institute of Science Education and Research, Bhopal, Centre National de la Recherche Scientifique, Institut de Chimie Moléculaire et des Matériaux d'Orsay

Language: English

Topic: Catalytic Alkyne Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green