Work

Growth differentiation factor 15: a promising biomarker in oral cancer

Year: 2025

Type: article

Abstract: Growth differentiation factor 15 (GDF-15), a cytokine within the transforming growth factor-β superfamily, is involved in various malignancies, with implications in oral squamous cell carcinoma (OSCC). Elevated GDF-15 levels are correlated with unfavorable prognosis, tumor progression, and chemotherapy resistance, and the protein has been identified as a potential diagnostic and prognostic biomarker for OSCC. Personalized treatment strategies based on GDF-15 expression could improve treatment outcomes.

Source: 대한구강악안면외과학회지

DOI: 10.5125/jkaoms.2025.51.2.123

Authors: Hyun Jun Oh, Jong-Ho Lee, Soung Min Kim

Institutions: Seoul National University, Seoul National University Dental Hospital

Language: English

Topic: GDF15 and Related Biomarkers

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: National Research Foundation, National Research Foundation of Korea, Ministry of Science and ICT, South Korea