Work

Rare paracholedochal lymph node metastasis in lung cancer

Year: 2025

Type: article

Abstract: Lung cancer remains the leading cause of cancer-related mortality worldwide. Common metastatic sites include the liver, bones and adrenal glands, while intra-abdominal lymph node metastases (ALNM) are less frequently recognized and often underestimated. Non-small cell lung cancer (NSCLC) accounts for 85% of lung cancer cases. Gastrointestinal and intra-ALNM are rare but likely underdiagnosed, with hematogenous and lymphatic pathways, including the thoracic duct, playing key roles. ALNM occurs in 6%-11% of NSCLC patients, with the porta hepatis being an exceptionally rare site. Advanced staging and follow-up are crucial for detecting ALNM, as they impact prognosis and therapy. Positron emission tomography/computed tomography (PET/CT) has shown superior sensitivity compared to CT in detecting extrathoracic metastases, influencing management in up to 25% of NSCLC cases. Here, we present the case of a NSCLC patient with a paracholedochal lymph node metastasis and explore various metastatic pathways emphasizing the pivotal role of PET/CT imaging.

Source: Journal of Surgical Case Reports

DOI: 10.1093/jscr/rjaf260

Authors: Tomás Marín-Cuartas, Jörg-Peter Ritz, Andreas Getz, Michael Wöhlke, Judith Sporn

Institution: Helios Hospital Schwerin

Language: English

Topic: Metastasis and carcinoma case studies

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,000