Year: 2025
Type: book-chapter
Abstract: Screening of genetic or chemical perturbations is a pragmatic approach to answering research questions that makes minimal prior assumptions. It is an approach that finds application in both academic discovery research and within pharmaceutical research and development. High content screening specifically utilises cell-based biology, and all of the complexity that affords, coupled with microscopy and data analysis to enable a huge range of questions to be addressed in all manner of inventive ways. With the increasing availability of automation, it has never been easier for research groups, institutes and companies to undertake large image-based screening campaigns. So what could go wrong? Let us count the ways…
Authors: S. Warchal, O. Song, R. Instrell, B. Marzook, M. Jiang, C. Queval, J. Tuersley, H. Saville, A. Sateriale, M. Howell
Institution: The Francis Crick Institute
Language: English
Subfield: Biophysics
Domain: Life Sciences
Open Access status: bronze
Awards: G2336958840, G4476224079, G4679252298
OpenAlex ID: W4409968482