Year: 2025
Type: article
Abstract: Mass Spectrometry Imaging (MSI) builds upon conventional mass spectrometry by allowing molecular distributions to be visualised directly from a sample surface. Unlike traditional approaches that require homogenisation and extraction, MSI captures mass spectra at defined spatial coordinates, building detailed molecular maps. Technological advancements in MSI have enabled very high spatial resolution and faster acquisition speeds. These developments have expanded MSI’s applications across biomedical research, pharmaceutical development, and forensic analysis, establishing it as a powerful tool for spatial-omics and molecular imaging.
Source: The Biochemist
DOI: 10.1042/bio_2025_110
Authors: Georgia M. Millard, Rohith Krishna, Sophie M. Pearce, Laura M. Cole, Simona Francese
Institution: Sheffield Hallam University
Language: English
Subfield: Spectroscopy
Field: Chemistry
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4409971434