Periodontal Disease and Age-Related Maculopathy: A Case Report
Year: 2025
Type: article
Study design: Case Report
Abstract: Age-related macular degeneration (AMD) is a leading cause of significant vision impairment in individuals aged 50 and older, primarily impacting central vision. This study seeks to investigate potential associations between periodontal disease and age-related maculopathy in the analyzed clinical case. A male subject of 66 years old, with age-related degenerative maculopathy and severe periodontal disease, was evaluated and treated. After an initial phase of non-surgical causal periodontal therapy, the periodontal indices were re-evaluated. In addition, the extraction of hopeless teeth replaced by dental implants was performed. A retinal topography was used to assess possible regression of the pathology, and proper anti-VEGF therapy was administered. The results showed a regression of periodontal disease and an improvement of the degenerative maculopathy. These preliminary results, even if encouraging, should be supported by larger prospective trials.
Authors: Francesco Mattia Ceruso, Stephany Gabriela Zambrano Leon, Luca Fiorillo, Gabriele Cervino, Marco Cicciù, Artak Heboyan, Francesco Pernice, Silvio Meloni, Marco Tallarico
Language: English
Subfield: Periodontics
Field: Dentistry
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,650
OpenAlex ID: W4409973368
