Work

Seborrheic Keratosis with Bowenoid Transformation

Year: 2025

Type: article

Abstract: A 30-year-old male presented with multiple, raised, hyperpigmented lesions on the penis and scrotum for 6 months. Physical and dermoscopic examinations revealed verrucous papules with distinct patterns. The histopathology report was consistent with the diagnosis of seborrheic keratosis (SK) with bowenoid transformation. Human papillomavirus (HPV) typing revealed HPV 6. Initial treatment with imiquimod 5% did not have any response. Later radiofrequency ablation led to complete resolution of lesion. SK, a benign epidermal tumour, is linked to factors such as sun exposure, HPV and genetic mutations. Studies suggest a potential for malignant transformation in SK, especially with HPV 6, as seen in this case, underscoring the need for patient follow-up and counselling.

Source: Indian Journal of Postgraduate Dermatology

DOI: 10.25259/ijpgd_73_2024

Authors: Siddharth Mani, Aradhana Rout, Manish Khandare, Hitesh Mahto

Institutions: Indian Navy, Command Hospital Air Force, All India Institute of Medical Sciences Bhopal

Language: English

Topic: Nonmelanoma Skin Cancer Studies

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4409974907

FWCI:

Cites: 8

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Related to: 10