Synchronous Metastasis of Renal Cell Carcinoma Presenting as a Primary Breast Tumor: A Rare Case Report
Year: 2025
Type: article
Study design: Case Report
Abstract: In the context of cancer prevalence in India, breast cancer is the most common leading site for women, followed by cervical cancer.1 Globally, kidney cancer accounts for approximately 2% of all neoplasms and cases of extramammary malignancies metastasizing to the breast are extremely rare occurring in only 0.5-2% of cases2. Metastatic renal cell carcinoma to the breast presenting as a breast primary is a rare entity and very few sporadic cases are mentioned in the literature3. The article discusses a specific case involving a 70-year-old woman who presented with a right breast lump of short duration that was initially diagnosed as invasive breast carcinoma through a core needle biopsy. However, further radiological investigations revealed a large exophytic mass in the right kidney. After a multidisciplinary discussion, the case was determined to be a dual primary cancer, leading to a surgical treatment plan that included a lumpectomy with sentinel node biopsy and nephrectomy. The histopathological examination ultimately confirmed that the breast lump was a metastatic renal cell carcinoma, highlighting the rarity of such occurrences.
Institution: Kokilaben Dhirubhai Ambani Hospital
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4409981534