Work

Beyond Glycaemia

Year: 2025

Type: article

Abstract: Background: Diabetes is a complex multifactorial disease. Therapy focused only on managing glycaemia does not yield optimal health outcomes. Health-related Quality of Life (HRQOL) is a broad, subjective, and multidimensional concept gaining significance in diabetes care. The complex interplay of HRQOL and other factors must be addressed to achieve optimal health outcomes. Objective: We aim to describe the factors associated with HRQOL in type 2 diabetes. Methodology: A single-center cross-sectional short messaging service (SMS) survey invited adults with type 2 diabetes (T2D) with ≥1 clinic attendance in the past year. Participants completed the Problem Areas in Diabetes-5 (PAID-5), Diabetes Distress Scale-17 (DDS17), and European Quality of Life Score (EQ-5D-5L). Demographic and diabetes-related data were retrieved from electronic medical records. Multiple regression models were created with EQ-5D-5L Index score (HRQOL) as the dependent variable. Result: , and HbA1c 8.0 (1.4)%. Of these, 60.9% had ≥1 microvascular and 23.8% had ≥1 macrovascular complication. Mean (SD) of EQ-5D-5L Index score was 0.81 (0.27), EQ5D Visual Analog Score (VAS) was 77.4 (23.8), total mean DDS17 score was 1.87 (0.93) and PAID-5 score was 5.04 (4.5). 26.9% and 11.3% had significant diabetes distress (DD) based on PAID-5 ≥8 and DDS17 ≥3. Multiple regression models revealed diabetes distress, a lower class of housing type, presence of macrovascular complication, higher BMI, older age, and female sex to be associated with a poorer EQ-5D-5L Index Score. Conclusion: Multiple non-glycemic factors like sociodemographic, socioeconomic, diabetes distress, impact health-related QoL in people with type 2 diabetes.

Source: Journal of the ASEAN Federation of Endocrine Societies

DOI: 10.15605/jafes.040.01.19