In vitro Antibacterial Efficacy of Various Root Canal Sealers Against Enterococcus Faecalis
Year: 2025
Type: article
Abstract: A BSTRACT Objective: The objective of this in vitro study is to evaluate and compare the antibacterial effectiveness of different root canal sealers against Enterococcus faecalis . Materials and Methods: The antibacterial efficacy of four root canal sealers—three bioceramic materials (TotalFill Bioceramic Sealer, BioRoot Root Canal Sealer, and MTA Fillapex) and one epoxy resin-based sealer (AH Plus)—against E. faecalis (ATCC 29212) was assessed using a modified direct contact test. Every sealer was made under the manufacturer’s instructions, and its antibacterial activity was evaluated against newly mixed and set sealers (1 and 3 days) at various intervals (2, 5, 20, and 60 min). Mitis salivarius agar was used to plate the bacterial suspension, and one-way ANOVA was used for statistical analysis. Results: TotalFill Bioceramic Sealer showed the highest antibacterial efficacy, followed by BioRoot Root Canal Sealer, MTA Fillapex, and AH Plus. Conclusion: Bioceramic root canal sealers, particularly TotalFill, demonstrate superior antibacterial efficacy against E. faecalis compared to epoxy resin-based sealers such as AH Plus.
Authors: Maneesha Das, Prachi Joshi, Arpita Hasmukhlal Jariwala, Sheetal Shivaji Patil, Aditi Singh, Debkant Jena
Language: English
Subfield: Oral Surgery
Field: Dentistry
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $250
OpenAlex ID: W4409993158