Gastric Adenocarcinoma Revealed by a Left Ventricular Thrombus: A Case Report and Literature Review
Year: 2025
Type: article
Study design: Case Report
Abstract: Background: Thromboembolic events are common in gastrointestinal malignancies, particularly in the context of Trousseau's syndrome. However, left ventricular (LV) thrombus as an initial presentation of gastric adenocarcinoma is extremely rare. Case Summary: We report the case of a 67-year-old man with a history of chronic smoking and chronic obstructive pulmonary disease, who presented with dyspnea, dry cough, fatigue and weight loss. Diagnostic imaging revealed a mobile thrombus in the left ventricle, without underlying cardiomyopathy or arrhythmia. Further investigation, prompted by the unexplained thrombus, revealed elevated tumor markers and an antral gastric wall thickening. Upper gastrointestinal endoscopy with biopsy confirmed the diagnosis of gastric adenocarcinoma. Anticoagulation therapy with low-molecular-weight heparin was initiated, followed by long-term anticoagulation. Echocardiographic follow-up demonstrated partial regression of the thrombus. Conclusion: This case highlights the importance of considering occult malignancy, particularly gastric cancer, in patients presenting with unexplained cardiac thrombi. A multidisciplinary approach is essential for timely diagnosis and optimized management.
Source: SAS Journal of Medicine
Authors: Malak El Adraoui, Mohammed Eljamili, Mustapha El hattaoui
Language: English
Topic: Cardiac tumors and thrombi
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4410014105