Placentrex and Ozonated Olive Oil: Emerging Modalities in Periodontal Healing – a Comparative Clinical Study
Year: 2025
Type: article
Study design: Clinical Trial
Abstract: Aim- To assess the clinical efficacy of Placentrex gel and ozonated olive oil in promoting healing following laser depigmentation .Materials and Methods - A split mouth study was conducted involving subjects with gingival melanin hyperpigmentation in the maxillary and/or mandibular arches.Each site was randomly assigned to one of two treatment groups.Laser depigmentation was performed under local anesthesia using a diode laser.Post procedure ,Group 1 received ozonated olive oil (Dentozone India),while Group 2 received Placentrex gel .Follow up evaluations were conducted at 1 week,2 weeks and 1 month postoperatively,assessing the Healing Index and Visual Analog Scale (VAS)scores for pain.Results- Both groups exhibited statistically significant reductions in VAS scores for pain and discomfort as well as improvements in healing at 1 and 2 weeks postoperatively. Notably ,the Placentrex group demonstrated superior healing and reduced pain at 15 days compared to the ozonated olive oil group. Conclusion- Laer depigmentation followed by the application of Placentrex gel may facilitate faster healing and reduced pain in individuals with gingival melanin hyperpigmentation.
DOI: 10.53555/kgsfez26
Authors: Dr.Ankita Garg, Satendra Sharma
Language: English
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4410017742