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Definitive Surgical Management of Refractory Amiodarone-Induced Thyrotoxicosis in a Cardiac Patient: A Case Report

Year: 2025

Type: article

Abstract: Amiodarone-induced thyrotoxicosis (AIT) presents a significant therapeutic challenge, particularly in patients with underlying cardiac comorbidities. We present a 58-year-old man with a background history of ischemic heart disease and atrial fibrillation who developed AIT following long-term amiodarone use. Despite the escalation of medical therapy, he remained clinically and biochemically thyrotoxic with symptomatic atrial fibrillation. Definitive management via total thyroidectomy was performed, resulting in clinical stabilization. This case highlights the importance of early multidisciplinary input and the role of total thyroidectomy in managing refractory AIT in high-risk cardiac patients.

Source: Cureus

DOI: 10.7759/cureus.83354

Authors: Islam Shah, Jonathan Fabricante, Fahas Ali Vattiyam Veettil

Institutions: Khyber Medical College, Khyber Teaching Hospital, Pakistan Army, Princess Alexandra Hospital NHS Trust, Princess Alexandra Hospital

Language: English

Topic: Thyroid Disorders and Treatments

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4410030266