Supplementary Tables S1-S5 from GPR65 Inactivation in Tumor Cells Drives Antigen-Independent CAR T-cell Resistance via Macrophage Remodeling
Year: 2025
Type: supplementary-materials
Abstract: Table S1: Differential expression and Activity analysis of human (h.CR vs h.NR) and mouse (m.CR vs m.PR) B-ALL tumor samples. The colum is ranked by combined Z-score of human and mouse DE results. Table S2: Functional enrichment analysis upregulated and downregulated genes in m.CR vs m.PR tumors RNA-seq. Table S3: Differential Expression analysis results of CART T cells treated with No tumor, CR tumors or GPR65 KO tumors. Table S4: Differential Expression analysis of GPR65 KO vs m.CR tumor cells from Day 7 Untreated, Day 11 Untreated and Day 11 CAR-T cell treated tumors. Table S5: NetBID2 Hidden driver analysis of 1035 TF comparing CAR T Treated GPR65 KO and CR tumors.
Language: English
Topic: CAR-T cell therapy research
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4410047685