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Discovery of a novel selenamide derivative as potent activator of aldehyde dehydrogenase 2 for cardioprotective applications

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Year: 2025
Type: article
Source: Medicinal Chemistry Research
DOI: 10.1007/s00044-025-03415-3
Authors: Yi Yang, Yue Yao, Junyang Huang, Zhan Shi, Xicheng Wang, Wei Li, Yishu Zhang, Jian Li, Yixiang Xu, Xiaokang Li
Institutions: East China University of Science and Technology, State Key Laboratory of Bioreactor Engineering, Shihezi University, Hainan University
Language: English

Topic: Aldose Reductase and Taurine
Subfield: Cell Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Innovative Research Team of High-level Local University in Shanghai, Natural Science Foundation of Shanghai, National Natural Science Foundation of China, National Key Research and Development Program of China
Awards: G1297229704, G1413700651, G2600120122, 基于老药的新型ALDH2*2激动剂发现驱动解酒护肝候选 新药研发
OpenAlex ID: W4410054039
FWCI:
Cites: 35
Cited by:
Related to: 10
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