Work

Clinical observations of features in spectrum domain optical coherence tomography of amiodarone-induced retinopathy: Two case presentation

Year: 2025

Type: article

Abstract: : Amiodarone is a class III anti-arrhythmic medication, which may result in possible ocular adverse effects. Amiodarone-associated retinopathy is infrequently perceived but is a potentially vision-threatening condition. We presented two rare cases of amiodarone-associated retinopathy. Their spectrum domain optical coherence tomography (SD-OCT) depicted loss of inner segment/outer segment (IS/OS) and cone outer segment tips (COSTs) lines at the macular region, sparing the external limiting membrane. One case exhibited additional hyperreflective spots at the subretinal layer on SD-OCT. Following the discontinuation of amiodarone and the administration of vitamin C eye drops, a partial recovery in the IS/OS and COST lines was observed.

Source: Taiwan Journal of Ophthalmology

DOI: 10.4103/tjo.tjo-d-23-00151

Authors: Chun Pao Chang, Hung-Chi Chen, An-Ning Chao, Laura Liu, Kuan-Jen Chen, Yi-Hsing Chen

Institutions: Chang Gung Memorial Hospital, Taoyuan Chang Gung Memorial Hospital, Linkou Chang Gung Memorial Hospital, Chang Gung University

Language: English

Topic: Drug-Induced Ocular Toxicity

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4410062708

FWCI:

Cites: 12

Cited by:

Related to: 10