Clinical significance of obesity measurement indicators and carotid artery plaques in type 2 diabetes
Year: 2025
Type: article
Study design: Observational Study
Abstract: INTRODUCTION: To investigate the clinical significance of obesity measurement indicators in patients with type 2 diabetes mellitus(T2DM) complicated with carotid plaque. METHODS: A total of 1009 subjects with T2DM were recruited in the cross-sectional study, and body measurements were collected. According to the results of carotid artery ultrasound, the study subjects were divided into T2DM without carotid plaque group (NCP: n = 617) and with carotid plaque group (WCP: n = 392). RESULTS: Compared with the NCP group, the waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), Chinese visceral fat index (CVAI), body roundness index (BRI), body fat index (BAI), body shape index (ABSI), and abdominal volume index (AVI) were significantly increased in the WCP group (P < 0.05). The results of multivariate stepwise logistic regression analysis showed that BAI, CVAI and ABSI had the greatest effect on carotid plaque (P < 0.05). After adjusting for multiple confounding factors, CVAI and ABSI remained independently associated with carotid plaques, and the combination of the three indicators exhibited superior predictive value for carotid plaques. CONCLUSION: CVAI and ABSI are closely related to the occurrence and development of carotid plaque in subjects with T2DM, and the combined application has a good effect on predicting carotid plaque.
Source: BMC Cardiovascular Disorders
Authors: Xia Chen, Xiuhui Zhang, Ziyan Sun, Ying Mao, Wentao Wu, Guoyue Yuan, Xia Deng
Institutions: Jiangsu University, Affiliated Hospital of Jiangsu University
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,090
Awards: G6348247475, G801245169
OpenAlex ID: W4410077310
