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Encapsulated papillary carcinoma: Diagnosis, treatment, and prognostic outcomes: A report of 2 case report

Year: 2025

Type: article

Abstract: RATIONALE: Encapsulated papillary carcinoma (EPC) is a rare subtype of breast cancer characterized by a favorable prognosis; however, its management can be complex, especially when associated with ductal carcinoma in situ (CIS) or invasive components. This study aimed to highlight the clinical presentation, diagnostic approach, and treatment outcomes of EPC to improve understanding and management strategies for this unique breast cancer subtype. PATIENT CONCERNS: We present 2 cases of elderly women who presented with breast lumps, prompting concerns regarding the nature of the lesions and the need for effective management strategies. DIAGNOSES: Case 1 involved a 67-year-old woman diagnosed with EPC within an inflammatory cyst wall, while case 2 was an 85-year-old woman with EPC and low-grade papillary CIS. Both diagnoses were confirmed through imaging and histopathological examination. INTERVENTION: Both patients underwent complete surgical resection of the tumors. Case 1 required no additional therapy postsurgery, while case 2 was monitored regularly without further treatment. OUTCOME: Both patients remained healthy following their respective interventions, with no evidence of recurrence noted during follow-up. LESSON: Early diagnosis and appropriate surgical intervention are critical in managing EPC. Regular monitoring is essential, particularly for cases with associated ductal CIS or invasive components, to ensure favorable outcomes.

Source: Medicine

DOI: 10.1097/md.0000000000042339