Work

Occurrence of papillary renal cell carcinoma and clear cell renal carcinoma in a patient: A unique case report

Year: 2025

Type: article

Abstract: RATIONALE: Renal cancer is one of the most common neoplasms in both males and females. Precise diagnosis, grading, and staging are very important for the outcome and the prognosis of the malignant process. Renal carcinoma disorders are presented by kidney tumors usually of the same histological type. The presence of various tumor histological types is an extremely rare event. PATIENT CONCERNS: Two different histological types of tumors were found in the left kidney of a 74-year-old man. DIAGNOSES: The diagnosis obtained was papillary renal cell carcinoma type 1 and clear cell renal carcinoma with pathologic stage T2N0M1. INTERVENTIONS AND OUTCOMES: After abdominal ultrasound and computer tomography, consultation with an anesthesiologist, and a cardiologist, the patient underwent radical left nephrectomy. LESSONS: Pathologists must be aware of the possibility of the presence of more than one histological type of renal carcinoma due to genomic alterations. Further genetic investigations must be conducted to identify the specific type and thus the treatment will be most precise.

Source: Medicine

DOI: 10.1097/md.0000000000042312

Authors: Zdravka Harizanova, Ferihan Popova, Vasil Pavlov, Elena Bozhikova

Institutions: Medical University Plovdiv, Mercer University

Language: English

Topic: Renal cell carcinoma treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,950