Year: 2025
Type: article
Abstract: The rapid emergence of antibiotic-resistant microorganisms often referred to as superbugs, has become a increasing global health concern. Vancomycin-Resistant Enterococci (VRE), Methicillin-Resistant Staphylococcus aureus (MRSA) and Multidrug-resistant Gram-negative bacilli (MDR-GNB) etc are the most deadly contagious strains. A significant portion of hospital-acquired infections can be caused by these superbugs. In health care, agriculture, and animal husbandry, antibiotics have been misused and overused, accelerating the development of antibiotic resistance. Antibiotic resistance continues to be a threat because bacteria with drug-resistant mechanisms are constantly developing new mechanisms to resist antibiotics. This study explores the rising threat of superbugs, drivers of antibiotic resistance and ineffective antibiotic treatments due to misuse of antibiotic, antibiotic over use in agriculture and environmental contamination stimulate resistant gene. A New Delhi metallo beta lactamase-1(NDM-1) is an enzyme leads to bacteria resistant which is a key factor in the emergence of antibiotic resistance. This urgent issue requires a multifaceted approach, including improved stewardship of existing antibiotics, investment in research for new treatments, and public awareness campaigns to promote responsible antibiotic use. The fight against superbugs is not only a medical imperative but also a societal responsibility that demands coordinated global action.
Authors: Md Tauseef Reza, Md Dilawar Shahnawaz, Shabnam Bashir, Suaad Khadeeja
Institution: Hemwati Nandan Bahuguna Garhwal University
Language: English
Subfield: Applied Microbiology and Biotechnology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W4410089744