Work

Evaluation of blood glucose lowering activity of Coffea robusta leaf extract in mice induced by alloxan

Year: 2025

Type: article

Abstract: An investigation of the antidiabetic activity of coffee leaf (Coffearobusta) extract in ethanol with doses 13,95, 27,9 and 55,8 mg/kg BW given orally to white male mice. Measurement of the blood glucose level was done day to-0, 8 and 18 using glucometer and glucotest strip. Doses variation of the ethanol extract coffee leaf showed that the dose of 27,9 mg/kg BW gave the best antidiabetic activity 59,61%. This experiment showed gave the best antidiabetic activity result gift ethanol extract coffee leaf. And Phytochemical screening ofthe ethanol extract coffee leaf showed the presence of alkaloids, phenols, saponnins, flavonoids and triterpenoids.

Source: GSC Biological and Pharmaceutical Sciences

DOI: 10.30574/gscbps.2025.31.2.0119

Authors: Rudi Kartika, Bohari, Subur P. Pasaribu, Aman Sentosa Panggabean, Daniel, Dirgarini Julia Nurlianti

Institution: Mulawarman University

Language: English

Topic: Natural Antidiabetic Agents Studies

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4410106379