Work

Patient Experiences and Treatment Satisfaction with Mini-Dose Glucagon as a Treatment for Hypoglycemia Following Repeated, Prolonged Fasts in Type 1 Diabetes During Ramadan

Year: 2025

Type: article

Abstract: Background/Objectives: Mini—dose glucagon (MDG) is a safe and effective option for managing hypoglycemia during prolonged, repetitive fasts in people with type 1 diabetes (pwT1D) during Ramadan. We aimed in this study to evaluate the effectiveness and patient satisfaction of MDG for the management of fasting—induced hypoglycemia from the perspective of pwT1D fasting during Ramadan. Methods: We conducted an online survey shared via social media platforms and email announcements from May 2021 to April 2023 to collect feedback from 136 (72 female) persons with T1D about their experiences using MDG. In the survey, participants were asked to answer questions about diabetes history, hypoglycemia management during Ramadan, the efficacy of MDG treatment, the psychological impact of breaking the fast, side effects, injection experiences, and preferred future treatments for hypoglycemia caused by fasting. Results: After using MDG, 123 (91%) of participants reported they were able to complete their fasts. A total of 110 (80%) of participants reported that they prefer to use MDG over oral options in the future to correct fasting—induced hypoglycemia. Furthermore, participants showed significant change in their habits, which would otherwise have left them exposed to hypoglycemia or hyperglycemia for longer periods of time during fasts. Conclusions: These data demonstrate positive user experience and satisfaction following MDG as a treatment for fasting—induced hypoglycemia in pwT1D. Furthermore, MDG can promote the successful completion of fasts in Ramadan and encourage a change in unhealthy habits that may lead to prolonged hypoglycemia during fasts.

Source: Journal of Clinical Medicine

DOI: 10.3390/jcm14093222

Authors: Metab Algeffari, Sufyan Hussain, Mansour Alsharidah, Salsabil Alkhalifah, Turki Almogbel

Institutions: Qassim University, King's College London, Guy's and St Thomas' NHS Foundation Trust, Kings Health Partners

Language: English

Topic: Diabetes Management and Research

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,137