AI-Assisted Design and Biochemical Optimization of Protein Structures for Enhanced Drug Delivery in Chemotherapy
Year: 2025
Type: article
Abstract: Chemotherapy remains the primary treatment for most malignancies; nevertheless, it is troubled by a handful of hindrances like non-specificity of the drug targeting agents, side effects, or actual drug resistance. Thus, protein engineering could be the answer to these problems by designing proteins capable of specific targeting of cancer cells, reducing unwanted drug toxicity, or carrying out controlled drug release. AI, in this regard, encompasses protein structure optimization for accelerated drug delivery and enhancement of the therapeutic efficacy. The present paper looks at AI utilization in protein engineering for drug delivery systems and its influence on chemotherapy, together with the possibility of using these innovations to combat existing challenges and enhance patient outcome.
Source: Journal of Neonatal Surgery
Authors: Kumaravel Kaliaperumal, Govindarajan S, Kamalam Ravi, Ian Pranandi, P Vinod Kumar, V M Gobinath
Language: English
Subfield: Computational Theory and Mathematics
Field: Computer Science
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4410124967