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A Rare Case of Autoimmune Hemolytic Anemia and Suspected Acute Hemorrhagic Disseminated Encephalomyelitis Following Recent Vaccination

Year: 2025
Type: article
Study design: Case Report
Abstract: Autoimmune hemolytic anemia (AIHA) and acute disseminated encephalomyelitis (ADEM) are rare autoimmune complications that may follow infections or vaccinations. We present a case of a 77-year-old male patient who developed warm AIHA and rapid neurological decline suggestive of hemorrhagic ADEM following recent varicella and influenza vaccinations. Laboratory findings confirmed AIHA, and MRI revealed multifocal white matter lesions with hemorrhagic foci. Despite high-dose corticosteroid treatment, the patient's condition worsened, and he ultimately passed away.
Source: Cureus
Authors: Hettiyadura Apsara Surangani Mendis Karunaratne, Karunakalage Anya A De Silva
Language: English
Subfield: Hematology
Field: Medicine
Open Access status: diamond
OpenAlex ID: W4410130255
FWCI: 0.654
Cites: 8
Cited by: 1
Related to: 10