Work

Efficacy and safety of ovarian vein embolization with N-butyl-2 cyanoacrylate for pelvic venous disorder: Analysis of 100 cases

Year: 2025

Type: article

Abstract: OBJECTIVE: The aim of this study was to evaluate the safety and efficacy of ovarian vein embolization using N-butyl-2 cyanoacrylate (NBCA) for treating pelvic venous disorder-associated chronic pelvic pain. METHODS: This retrospective study analyzed 100 patients who underwent ovarian vein embolization with NBCA at a single institution between February 2018 and June 2024. Pelvic venous insufficiency was confirmed by duplex ultrasound and abdominal computed tomography or magnetic resonance imaging, and NBCA was the sole embolic agent. Pain levels were assessed pre- and post-procedure using the Visual Analogue Scale (VAS) in three categories: pain on standing, dyspareunia, and menstrual pain. Follow-up included clinical evaluation and VAS scoring at 1 to 3 months and annually. Statistical analysis determined the significance of pain reduction. RESULTS: Technical success was achieved in all cases, with complete occlusion of the target veins. Clinical success was observed in most patients, with significant improvement in VAS scores across all categories (P < .05). Due to symptom recurrence, four patients (4%) required reintervention during follow-up. No NBCA-related complications were reported. CONCLUSIONS: In our study, ovarian vein embolization with NBCA appears to be a safe and effective treatment for pelvic venous disorder-associated chronic pelvic pain, providing significant pain relief. Additionally, it offers advantages over permanent metal implants such as the potential for gradual polymer degradation over time and avoiding interference in future imaging studies.

Source: Journal of Vascular Surgery Venous and Lymphatic Disorders

DOI: 10.1016/j.jvsv.2025.102256

Authors: Jose María Hipola, Alberto Alonso, Regina Cárdenas, Eugenia Pillado, Jose Ignacio Leal

Institution: Clinica Universidad de Navarra

Language: English

Topic: Diagnosis and Treatment of Venous Diseases

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,400