Single atom catalysts for electrocatalytic C–N coupling: From dynamic mechanism to rational design
Year: 2025
Type: article
Abstract: Electrocatalysis for C−N coupling reactions (EcnRR) plays a crucial role in the synthesis of various organic molecules. However, the C−N coupling process is inherently complex and kinetically sluggish. Single-atom catalysts (SACs), with their high atomic efficiency, tunable structures, and remarkable catalytic activity, exhibit exceptional performance and hold great promise for C−N coupling reactions. The design of SACs requires a deep understanding of the reaction mechanisms, particularly the dynamic evolution of multi-component reactions. This necessitates systematic studies of multi-species coupling mechanisms to move beyond traditional trial-and-error approaches. This review elucidates the activation mechanisms of carbon- and nitrogen-containing molecules, providing fundamental insights into the SACs-mediated electrocatalytic C−N coupling process. Notably, the core focus lies in proposing novel design principles for SACs systems tailored for C−N coupling, based on theoretical frameworks and experimental findings. These insights not only guide the improvement of existing methodologies but also offer transformative pathways for electrocatalytic organic nitrogenation via C−N coupling chemistry, potentially reshaping the landscape of organic synthesis. Looking ahead, a comprehensive understanding of the structure–activity relationships in SAC design will be key to advancing this rapidly evolving field.
Source: Nano Research
Authors: Chao Zhao, Wei Liu, Qilin Hou, Jingkang Yuan, Honghui Ou, Guidong Yang
Institution: Xi'an Jiaotong University
Language: English
Field: Energy
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $5,290
Awards: G1099530167, G153810238, G6451243684
OpenAlex ID: W4410135922