Work

The “H sign” in MOGAD myelitis

Year: 2025

Type: article

Abstract: A 40-year-old man presented with acute urinary retention and bilateral lower limb weakness. MRI revealed a longitudinally extensive T2 hyperintense spinal cord lesion from C6 to T10, predominantly involving the gray matter ("H sign"). Brain MRI and CSF studies were unremarkable. Serum MOG-IgG was positive. The patient was treated with intravenous corticosteroids, with subsequent clinical and radiologic improvement. The imaging and clinical findings were consistent with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD).

Source: Neurological Sciences

DOI: 10.1007/s10072-025-08160-4

Authors: Santiago Aristizabal Ortiz, Laura Andrea Campaña Perilla, Angela Patricia Guarnizo Capera

Institutions: Universidad El Bosque, Fundación Santa Fe de Bogotá

Language: English

Topic: Multiple Sclerosis Research Studies

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,090