Yag Laser-assisted Fragmentation of Dexamethasone Implants in the Anterior Chamber
Year: 2025
Type: article
Abstract: PURPOSE: To report efficacy on the use of neodymium yag laser in fragmentating dexamethasone intravitreal implant (Ozurdex, Allergan, Inc, Irvine, CA) migrated in the anterior chamber (AC). METHODS: Multicenter, retrospective, interventional case series of 10 patients treated with Nd:Yag laser following spontaneous migration of dexamethasone implant into the AC. RESULTS: The Nd:yag laser successfully fragmented the migrated implants in all cases without severe complications. No patient exhibited corneal edema at 4 months post-treatment. Visual acuity remained stable or improved in four patients, while one patient had minimal transient visual deterioration due to pre-existing retinal conditions. In all patients resolution of previous macular edema was detected. CONCLUSIONS: Spontaneous migration of the dexamethasone intravitreal implant into the anterior chamber can occur in patients with aphakia, prior pars plana vitrectomy, or compromised capsular support. Timely intervention using Nd:yag laser can effectively fragment the dexamethasone implant, mitigating the risk of corneal endothelial damage and preserving visual function. In this cohort Nd:yag laser appeared a safe and effective treatment option for managing anterior chamber migration of the dexamethasone intravitreal implant, avoiding the need for more invasive surgical techniques or temporary non-invasive techniques.
Source: Retina
Language: English
Topic: Retinal and Macular Surgery
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4410141183