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Successful treatment of endoxifen overdose: A case report

Year: 2025

Type: article

Abstract: Endoxifen is a direct protein kinase C inhibitor available in India for the management of bipolar disorder since 2021. Clinical studies show that endoxifen is as effective as divalproex sodium and has a good tolerability profile. Clinical data related to overdosage of endoxifen has not yet been reported. We hereby report the case of a 37-year-old female presenting with suicidal ingestion of 56 mg of endoxifen, leading to mild mania. No changes were observed in vital signs, laboratory parameters, electrocardiogram, or ophthalmic examination. This case report suggests a good tolerability profile of endoxifen.

Source: Indian Journal of Case Reports

DOI: 10.32677/ijcr.v11i4.5018

Authors: Nahid Dave, Sagar Karia

Institution: Lokmanya Tilak Municipal General Hospital and Lokmanya Tilak Municipal Medical College

Language: English

Topic: Poisoning and overdose treatments

Subfield: Emergency Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4410141184

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