Work

JAB-3312, a Potent Allosteric SHP2 Inhibitor That Enhances the Efficacy of RTK/RAS/MAPK and PD-1 Blockade Therapies

Year: 2025

Type: article

Source: Clinical Cancer Research

DOI: 10.1158/1078-0432.ccr-24-3691

Authors: Di Kang, Yanping Wang, Yiwei Lin, Wen Wee Ma, Daniel Morgensztern, Konstantinos Leventakos, Chao Bi, Yuli Ding, Jing Xiong, Man Yan, Xin Sun, Peng Wang, Cunbo Ma, Yinxiang Wang

Institutions: Cleveland Clinic, Washington University in St. Louis, Mayo Clinic, Mayo Clinic Comprehensive Cancer Center (Minnesota)

Language: English

Topic: Protein Tyrosine Phosphatases

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W4410156573

FWCI: 4.06

Cites: 79

Cited by: 16

Related to: 10