Year: 2025
Type: article
Study design: Clinical Trial
Abstract: : Food allergies can result in persistent and systemic hypersensitivity reactions that are often resistant to standard treatment methods. This study aimed to assess the clinical and immunological effectiveness of extracorporeal blood purification (EBP) in patients with refractory food allergies. A total of 42 patients with confirmed food allergies underwent three sessions of EBP using plasmapheresis and hemosorption. Significant reductions were observed in symptom severity, total serum IgE, eosinophil counts, histamine, and C-reactive protein levels. Quality of life improved notably as assessed by the Food Allergy Quality of Life Questionnaire – Adult Form (FAQLQ-AF). The treatment was well-tolerated, with only minor adverse effects. These results suggest that EBP may serve as a valuable adjunct therapy for food allergy patients who fail to respond to elimination diets and conventional pharmacotherapy.
Institution: Samarkand State Medical Institute
Language: English
Subfield: Immunology and Allergy
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4410157656