Work

Short-term maternal oxytocin administration may protect against poor outcomes of adverse childhood experiences in the offspring

Year: 2025

Type: article

Abstract: Adverse childhood experiences (ACEs), such as early-life adverse events experienced by the mother and fetus during pregnancy (e.g. physical harm or chronic stress) or at early postnatal time points (such as maternal neglect or maternal separation), are major risk factors for future behavioral impairments, including anxiety, heightened pain sensitivity, social impairment, and depression during adolescence and adulthood [1–4]. The long-lasting effects of these adverse experiences are thought to be partially mediated via modulation of the hypothalamic-pituitary-adrenal (HPA) axis [5–7].

Source: Neurotherapeutics

DOI: 10.1016/j.neurot.2025.e00605

Author: Elad Lax

Institution: Ariel University

Language: English

Topic: Neuroendocrine regulation and behavior

Subfield: Social Psychology

Field: Psychology

Domain: Social Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,900