Eutectic mixtures in the design of drugs
Year: 2025
Type: article
Abstract: Drug development is a stage of modern drug design aimed at improving the biopharmaceutical characteristics of drugs, such as solubility, chemical stability, bioavailability, and pharmacological activity. The synthesis of solid dispersed systems of the eutectic type is one of the alternative options for the creation of new medicines based on known active pharmaceutical substances with improved and predictable properties. Eutectic mixtures consist of two or more components, and are characterized by certain compositions and a low melting point. The features of the microstructure of eutectic affect its physico-chemical properties, which determines the potential use of these systems in the pharmaceutical industry. The article provides an overview of scientific research aimed at studying eutectic compositions and analyzing their characteristics: solubility and dissolution rate, therapeutic efficacy and technological properties.
Source: Aspirantskiy Vestnik Povolzhiya
DOI: 10.35693/avp677728
Authors: Anna N. Seryakova, Aleksandr Voronin
Institution: Samara State Medical University
Language: English
Subfield: Pharmaceutical Science
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4410164897